Every three to four minutes, someone in the U.S. is diagnosed with a blood cancer.

For patients with blood cancers like leukemia and other life-threatening blood diseases such as sickle cell—a cure exists. NMDPSM is a global nonprofit leader in cell therapy. For nearly 40 years, we’ve connected thousands of patients with donors like you for a life-saving blood stem cell transplant.

Four things to know before joining

This two minute video explains a few things you should know about blood stem cell donation and what being a member of the NMDP RegistrySM means.

Step up to save a life

You can join the NMDP Registry if you’re between 18 and 40. Research shows cells from younger donors give patients their best chance at surviving long term.
  • Hands are holding an NMDP swab kit. The kit features a picture of a smiling person swabbing, instructions and a barcode.

    1. Order your free swab kit

    Registering online is easy. You’ll answer a few questions to confirm you can join, then tell us where to mail your free swab kit (usually arrives in 3–7 days).
  • Woman with curly hair holding a swab in her mouth, sitting at a table with a swab kit. The background includes a Vancouver poster and a clock.

    2. Swab and send it back

    Follow the steps in the kit to swab your cheeks, then mail it back using the prepaid envelope. We’ll process your samples to add your tissue type to the registry.
  • Three young adults stand outside, looking at mobile phones and smiling. They are casually dressed in hoodies and appear to be on a college campus.

    3. Stay connected and ready

    Because matching is complex, some members are needed quickly, while others wait years. What helps patients most is that you stay committed each year and keep your contact information up to date.
A young woman in a hospital setting, wearing an "I'm a Donor" t-shirt, proudly holding a bag of donated blood stem cells.
Mariel, blood stem cell donor

Facts about blood stem cell donation

  • Most donors (90%) donate via peripheral blood stem cells (PBSC)—it's like donating plasma.
  • Some donors (10%) donate via marrow withdrawn from the hip bone while under anesthesia.
  • Discomfort and side effects of donating vary from person to person.
  • Most PBSC and bone marrow donors can return to their regular activities within 1–7 days.
  • You’ll likely be asked to travel within the U.S. to donate.
  • NMDP pays for all donation and travel costs, including flights, hotel stays and meals for you and a companion.
  • NMDP also covers missed pay from work, pet care and childcare.
  • Donating doesn’t impact your ability to have kids.
  • Every precaution is taken to ensure the safety and well-being of every donor.