What is a h​aploidentical transplant​?

A haploidentical (half-match) transplant is a type of allogeneic transplant that uses healthy blood-forming cells from a donor to replace the patient’s unhealthy ones. Haploidentical transplants are commonly used to treat forms of blood cancers and diseases, such as chronic myeloid leukemia or sickle cell disease.

A haploidentical transplant is often called a half-match transplant because exactly half of the donor’s HLA markers match the patient.

• Parents are always a half-match for their children, and vice versa.
• Siblings have a 50% chance of being a half-match.
• Other relatives (cousins, aunts, uncles) are unlikely to be half-matched donors.

Because haploidentical transplants use family members as donors, they provide a potential cure for more patients who lack a fully matched donor.

Learn what it means to be a family donor

As you consider haploidentical transplant it’s important to ask your doctor:

• Is a haploidentical transplant an option for me?
• What are the risks and benefits of transplant from a haploidentical donor compared to other types of donors?
• How much experience does this transplant center have performing half-match transplants?
• What are the typical results for patients at this center who have had a transplant from a half-matched donor?
• Is there a haploidentical transplant clinical trial that I could join?
• Which family member would be my half-matched donor? What does that person have to do?

We know how important it is to make the right choice when it comes to choosing a treatment option. That’s why we’ve created a full list of questions to ask your transplant team that’ll give you all the information you need to begin treatment with confidence.

Your health insurance company may cover some of or the majority of your transplant expenses. When considering a haploidentical transplant, ask your health insurance provider these questions to help yourself better understand how paying for your transplant will work:

Does my health insurance policy pay for:

• An allogeneic transplant from a haploidentical donor?
• Care in a haploidentical transplant clinical trial?
• My family member’s bone marrow or peripheral blood stem cell collection?

As you begin to understand the financial aspects for transplant, there are additional questions to ask your health insurance company.

If you have questions about whether haploidentical transplant is right for you, talk with your transplant doctor. Every person’s situation is different, and your transplant doctor can help you determine the most effective treatment option.

Explore the full range of services we provide for patients considering a half-match transplant, including group support, emotional and spiritual support, tips for healthy living after transplant and more.